Basic Information
VIS ID
TVIS10003376
Fusion event
HBV-chr19 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
q13.41
Reference genome
GRCh37/hg19
Start
52731682/52228429 (Hg38)
End
52731682/52228429 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-let-7e/Upstream/6331; hsa-mir-10394/Downstream/53368;
Nearest TSS
ENST00000633603/Upstream/7446; ENST00000600016/Downstream/2858;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/38001, chr19-CpG: 47/Downstream/41136
Nearby gene
PPP2R1A(-2004) ; ZNF766(+41142) ;
Nearest cancer related gene
PPP2R1A(OG, -2004) ;
Upstream sequence
CCTGAGTTAACCAGGAGTTGCCTGGtgtcttgggtcatgtgctctagaagcagagcccgagtggagactcgttcaagtgtgttactgagggagtgctctc
Downstream sequence
aggagaaCGGACTGAGGTAACTCACCTTCTGTGAGCTTCATGTTGGAAGAATCCAATCAGGTGATGAATGTGATGTTATTAAGTCCATTGTTAGGAGTGG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate