RIMBP2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003390
Fusion event
HBV-RIMBP2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
q24.33
Reference genome
GRCh37/hg19
Start
130923006/130438461 (Hg38)
End
130923006/130438461 (Hg38)
Location type
Exonic
Fragile sites / regions
FRA12E
Target gene
RIMBP2
miRNAs that regulate target gene
hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4286 ; hsa-mir-330-3p
Nearest miRNA
hsa-let-7i/Upstream/2144283; hsa-mir-6763/Downstream/2143536;
Nearest TSS
ENST00000382841/Upstream/17442; ENST00000443685/Downstream/40502;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/13815, chr12-CpG: 20/Downstream/12706
Upstream sequence
CACCCTCTGCCCTTTGGCATACACGCCGTAGCCGGTAACGTTTGCGCCATTGGACAGCCCGGTGGGCGTCAGCACAGGTGGTCTCCAGGAGACCCGGATG
Downstream sequence
GTGGCGGGGGTCACCCCAGCCTGGACGGTAACATCTTGTGGGGGTGCTGGGGGTCCTGGGAGGGGACAGAAGGGAACGGAGGCGTTCAGGGACCAGCCCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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