Basic Information
VIS ID
TVIS10003396
Fusion event
HBV-SWT1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
185218692/185249560 (Hg38)
End
185218692/185249560 (Hg38)
Location type
Intronic
Target gene
SWT1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-19b-3p
Nearest miRNA
hsa-mir-101-1/Upstream/4811170; hsa-mir-1182/Downstream/7466768;
Nearest TSS
ENST00000473358/Upstream/92078; ENST00000609881/Downstream/51358;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/91987, chr1-CpG: 114/Downstream/66637
Upstream sequence
ACatccccaagtcttatccctttataggattaggttaaagtccagaatctcattatttgaatcaggtccaggtgtgattgaggcaaggctccctgggtat
Downstream sequence
ggctccttcagcagagctccttgagtacctaccgttcctctagatgggaagtgctgtgaactaaagagacaaactgatcccccaccacccaccccatact
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate