Basic Information
VIS ID
TVIS10003405
Fusion event
HBV-PDXDC2P integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
70081297/70047394 (Hg38)
End
70081297/70047394 (Hg38)
Location type
ncRNA_intronic
Fragile sites / regions
FRA16B
Target gene
PDXDC2P
Nearest miRNA
hsa-mir-1225/Upstream/16972; hsa-mir-11401/Downstream/6821542;
Nearest TSS
ENST00000527434/Upstream/95653; ENST00000561920/Downstream/66232;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/81520, chr16-CpG: 96/Downstream/17977
Upstream sequence
ctcaaggacaaaacaacaaacaccacatgttctcactcataggtgggaattgaacaatgagactacatggacacaggaaggggaacatcatacactgttg
Downstream sequence
cttgttgtggggtggggggagggaggagggatagcattaggagatatacctaacgttaaatgaagagttaatgggtgtggcacaccaacatggcacatgt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate