Basic Information
VIS ID
TVIS10003428
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
10039/10039 (Hg38)
End
10039/10039 (Hg38)
Location type
Promoter;downstream
Fragile sites / regions
FRA1A
Target gene
DDX11L1 ; MIR6859-1 ; MIR6859-2 ; WASH7P
Nearest miRNA
hsa-mir-101-1/Downstream/7330;
Nearest TSS
ENST00000473358/Downstream/19515;
Nearest CpG islands
None/Target, None/Upstream, chr1-CpG: 111/Downstream/18696
Upstream sequence
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNtaaccctaaccctaaccctaaccctaaccctaaccctaa
Downstream sequence
ccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaacccaaccctaaccctaaccctaaccctaacccta
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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