Basic Information
VIS ID
TVIS10003438
Fusion event
HBV-OR4F21 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
124397/174397 (Hg38)
End
124397/174397 (Hg38)
Location type
Promoter
Target gene
OR4F21
Nearest miRNA
hsa-mir-10400/Downstream/1626728;
Nearest TSS
ENST00000518652/Upstream/7354; ENST00000610248/Downstream/57740;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/90903, chr8-CpG: 25/Downstream/54604
Upstream sequence
ttcgtgtactttgatattttatgtacagtatataatatgtaattggtgtaatttgatattttatgttcagtatataatatgtatttggtgtactttttga
Downstream sequence
CTCACCGATTTACTAAGTATAGATTTTATTTCTATCCCTCACCTACCTGTTTTGCCAAGGGAACTAAGAAAAGAGCATCATCAAAAATTCAGATAGGTAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate