Basic Information
VIS ID
TVIS10003443
Fusion event
HBV-GTF2IP13 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
45821236/45781637 (Hg38)
End
45821236/45781637 (Hg38)
Location type
Intronic
Target gene
GTF2IP13
Nearest miRNA
hsa-mir-1183/Upstream/899837; hsa-mir-10399/Downstream/11174148;
Nearest TSS
ENST00000635602/Upstream/97252; ENST00000457280/Downstream/91445;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/12491, chr7-CpG: 74/Downstream/106766
Nearby gene
SEPTIN7P2(-12619) ; IGFBP1(+106723) ;
Upstream sequence
aggctggagtgcagtggcacgatcttggctcactgtaagctccacctcctgggttcacgccattctcctgcctcagcctcccgagtagctgggaccacat
Downstream sequence
AATAGTATGCCTCTAAGTATTAATTATGTCCTAGGACAGGAGAATTCATGTTGTCAAAATTCTCATACTCTCTAGAACAATAAACTCATTTTCTTTTTAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate