Basic Information
VIS ID
TVIS10003449
Fusion event
HBV-chr5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
GRCh37/hg19
Start
161086390/161659384 (Hg38)
End
161086390/161659384 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/1173934; hsa-mir-103a-1/Downstream/6506461;
Nearest TSS
ENST00000502646/Upstream/27654; ENST00000524220/Downstream/26173;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/111006, chr5-CpG: 26/Downstream/1777994
Nearby gene
GABRB2(-111260) ; GABRA6(+26268) ;
Upstream sequence
TGGAGTAATTAACACCATGTGCATGGCGAGGAAACGCCTCCCGGCATTCAATGAAGATCGCTGATACCCAGAAGACACCCCAGTATTATGGGTGCAGTTA
Downstream sequence
gacctaaaaaaaagtaaagaatttgaattagtaataaaaataattctcatagagaaaaactctggcccatatctctttactggtatgttctaccttaatt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate