Basic Information
VIS ID
TVIS10003450
Fusion event
HBV-LOC107986678 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q27
Reference genome
GRCh37/hg19
Start
170941325/170632237 (Hg38)
End
170941325/170632237 (Hg38)
Location type
Intronic
Target gene
LOC107986678
Nearest miRNA
hsa-mir-10398/Upstream/301393;
Nearest TSS
ENST00000381078/Upstream/47545; ENST00000448824/Downstream/63076;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/19550, chr6-CpG: 91/Downstream/80164
Nearby gene
PDCD2(-47545) ;
Upstream sequence
aggtgggcaacttggaaaacaagtgcagtgtttaactctgaccctaggacttcataggcttgcccctttcccatgattcttcccttagggtgtgctgccc
Downstream sequence
AAGGTCTGTGACTGGCAATGAGTGAATTACATTCTCCTCAGTTGGGTGCAATGTCTGCCTTCTGTGTGGCCATTTGCTGTTGCCACTAGAGAAGGAGGAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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