Basic Information
VIS ID
TVIS10003471
Fusion event
HBV-VIRMA integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
95521881/94509653 (Hg38)
End
95521881/94509653 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
VIRMA
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-12123/Upstream/593534; hsa-mir-10400/Downstream/563258;
Nearest TSS
ENST00000518652/Upstream/13217; ENST00000521010/Downstream/1909;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/34520, chr8-CpG: 34/Downstream/43776
Upstream sequence
actgtagcctggaattcctggttcaagggtttaagtgatccttttgccctcctgagtagctgggactacaggtgtgtgccaccatgccttgctaatCAAA
Downstream sequence
GCAGAGAGAGACTTTATAAAATAACTATAAATACCTGATCACAGAGAGACTGCAAAATGGATGTGACATATTCAACACACTGTTGGCGAATAACACTGTC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate