Basic Information
VIS ID
TVIS10003484
Fusion event
HBV-ADTRP integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
11735794/11735561 (Hg38)
End
11735794/11735561 (Hg38)
Location type
Intronic
Target gene
ADTRP
Nearest miRNA
hsa-mir-3691/Upstream/1295767; hsa-mir-10398/Downstream/4405995;
Nearest TSS
ENST00000381078/Upstream/7004; ENST00000412132/Downstream/95;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/196865, chr6-CpG: 37/Downstream/273539
Upstream sequence
cgtcagccaagatcgtgccaatgcatccagcctgggtgacagagtgagactctgtctcaaaaaaaaaaaaaaaaaaaaaGCCTTAACTTTTTTACCACCT
Downstream sequence
TCTTACCGGCTGATGTAAGCAATGCTGGCAGCAGCCAGCAAGGTGAGTCCTGTCTTCTTTGATGGATAGGAGTGAGGCCTGAGGACGACTTCAGCCAATG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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