Basic Information
VIS ID
TVIS10003487
Fusion event
HBV-KAZN integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p36.21
Reference genome
GRCh37/hg19
Start
14533497/14207002 (Hg38)
End
14533497/14207002 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
KAZN
Nearest miRNA
hsa-mir-12136/Upstream/1627979; hsa-mir-101-1/Downstream/2651947;
Nearest TSS
ENST00000473358/Upstream/314210; ENST00000376028/Downstream/16116;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/313760, chr1-CpG: 116/Downstream/391112
Nearby gene
PRDM2(-381923) ; KAZN(+391716) ;
Upstream sequence
aaaTGGTAGAGTAAATGATTCTGTGCATTTCTACATCCTTTCTTTTCTTCttctttttctttctttctttttttttttgagatggagtttcactcttgtt
Downstream sequence
gcccaggctggagggcagtggtgtaatctcagctcactgcaacttctgcctctcgggttcaagtgattctcctgcctcagcctctcaagtagctgggatt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate