Basic Information
VIS ID
TVIS10003521
Fusion event
HBV-chr8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
53698062/52785502 (Hg38)
End
53698062/52785502 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/9889227; hsa-mir-10400/Downstream/8929286;
Nearest TSS
ENST00000518652/Upstream/39659; ENST00000331251/Downstream/152929;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/70561, chr8-CpG: 235/Downstream/153639
Nearby gene
RB1CC1(-71036) ; NPBWR1(+154406) ;
Nearest cancer related gene
RB1CC1(TSG, -71036) ;
Upstream sequence
TGAGTAATGCAGTGCCATTCCGAGGGTGATGCAGGTGATTCGAGCCTTCCTACTACTTGGCCCTTGTCCTTGGGTTGGTATTGCTTGTCTACCTCTCGTA
Downstream sequence
agagtgaaactccatctcaaaaaaaaaagaaagaaagaaagaaagaaaATAGCATTACAAAACTGAAGAGATTACAATACTGGTCTCACCATCATTTTTA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate