Basic Information
VIS ID
TVIS10003542
Fusion event
HBV-chr7 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q33
Reference genome
GRCh37/hg19
Start
137860783/138176037 (Hg38)
End
137860783/138176037 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/52216; hsa-mir-10399/Downstream/868063;
Nearest TSS
ENST00000635602/Upstream/12597; ENST00000485318/Downstream/284297;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/173727, chr7-CpG: 146/Downstream/283885
Nearby gene
MIR4468(-52216) ; TRIM24(+284296) ;
Nearest cancer related gene
TRIM24(TSG, +284296) ;
Upstream sequence
ccgcctcggcctcccaaagtgctgggattacaggcatgagccaccacgcctggccTCCCAGTGTCTTTTATGACTTCACTTCCTCGCCCTCTTCTCACCT
Downstream sequence
aaAAAGAAAATTCAATTTGGGAAAaacaaacgaaaacagatgggtaaagtaggcagaaagatgaaaaccctaagaaagaatcaaaaggaaatgttagaaa
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate