Basic Information
VIS ID
TVIS10003545
Fusion event
HBV-chr5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
GRCh37/hg19
Start
161429517/162002511 (Hg38)
End
161429517/162002511 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/1517061; hsa-mir-103a-1/Downstream/6163334;
Nearest TSS
ENST00000502646/Upstream/1315; ENST00000639549/Downstream/34260;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/454133, chr5-CpG: 26/Downstream/1434867
Nearby gene
GABRA1(-102552) ; GABRG2(+65131) ;
Upstream sequence
taaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaat
Downstream sequence
acaagagtgaaactccatctcaaaaaaaaaaaaaaagaaagaaagaaaaTGCCAGAGTTTTGTTGACTCAAACGAAATTACCTAAAGCATTTTTCACATT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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