VISDB Viral Integration Site DataBase

VIS ID

TVIS10003551

Fusion event

HBV-chr2 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr2

Cytoband

q37.1

Reference genome

Start

End

232330716/231466005 (Hg38)

Location type

Promoter

Target gene

NCL ; SNORD20 ; SNORD82

miRNAs that regulate target gene

hsa-mir-30a-5p ; hsa-mir-877-3p ; hsa-mir-744-5p ; hsa-mir-615-3p ; hsa-mir-598-3p ; hsa-mir-92b-3p ; hsa-mir-193b-3p ; hsa-mir-221-3p ; hsa-mir-197-3p ; hsa-mir-92a-3p ; hsa-let-7c-3p ; hsa-mir-548t-3p ; hsa-mir-548aa ; hsa-mir-548ap-3p ; hsa-mir-3674 ; hsa-mir-135b-3p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-mir-8065 ; hsa-mir-3148 ; hsa-mir-4496 ; hsa-mir-942-3p ; hsa-mir-4802-3p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-493-5p ; hsa-mir-6728-5p ; hsa-mir-5187-5p ; hsa-mir-494-3p ; hsa-mir-338-5p ; hsa-mir-874-3p ; hsa-mir-3157-3p ; hsa-mir-5681b ; hsa-mir-6886-3p ; hsa-mir-4780 ; hsa-mir-938 ; hsa-mir-708-3p ; hsa-mir-203a-3p ; hsa-mir-105-5p ; hsa-mir-3153 ; hsa-mir-3671 ; hsa-mir-3688-3p ; hsa-mir-4694-3p ; hsa-mir-5584-5p ; hsa-mir-607 ; hsa-mir-6124 ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-7853-5p

Nearest miRNA

hsa-mir-10b/Upstream/103212; hsa-mir-1244-1/Downstream/247309;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/567, chr2-CpG: 41/Downstream/17667

Upstream sequence

tcccagctactcgggaggctgaggtgagaggatcgcttgagcccaggaggcggaggttgcagtgagccgagatcgcgtcattgaactccagcctgaggaa

Downstream sequence

caagagcgaaaccccatctcaaaaaaaaaaaaaagaaagaaaataaaaTTATTTGTTAAATGAATGAAGTATTTAGGTAGAAGCAGCAGCAGGGAGAGCC