PRKACA _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003611
Fusion event
HBV-PRKACA integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
p13.12
Reference genome
GRCh37/hg19
Start
14210505/14099693 (Hg38)
End
14210505/14099693 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
PRKACA
miRNAs that regulate target gene
hsa-mir-22-3p ; hsa-mir-744-5p ; hsa-mir-196b-5p ; hsa-mir-331-3p ; hsa-mir-365a-3p
Nearest miRNA
hsa-mir-10395/Upstream/26214; hsa-let-7e/Downstream/429850;
Nearest TSS
ENST00000633603/Upstream/1228; ENST00000590715/Downstream/1585;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/8141, chr19-CpG: 98/Downstream/17984
Upstream sequence
tttttttttttttgtatttttttgtagagatggggtcttgctatgtaaggctggtctcaaattcctgggctctagcaatctgcccaccttggcctcccca
Downstream sequence
agtgggattatagggcatgagccacagtacccagccTGTATCTTAAACTTACAAATTTCTGTATATAGatttattttatgtataaaaatatatattaaaa
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate