Basic Information
VIS ID
TVIS10003620
Fusion event
HBV-MFSD14C integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
99722198/96959916 (Hg38)
End
99722198/96959916 (Hg38)
Location type
ncRNA_intronic
Target gene
MFSD14C
miRNAs that regulate target gene
hsa-mir-887-3p ; hsa-mir-4294 ; hsa-mir-924 ; hsa-mir-4635 ; hsa-mir-1273g-3p ; hsa-mir-550b-2-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-7703 ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-542-3p ; hsa-mir-661 ; hsa-mir-6743-3p ; hsa-mir-6776-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6742-3p ; hsa-mir-6849-3p ; hsa-mir-508-5p ; hsa-mir-8057 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-1304-3p ; hsa-mir-6890-3p
Nearest miRNA
hsa-let-7a-1/Upstream/1873822; hsa-mir-12126/Downstream/403638;
Nearest TSS
ENST00000422679/Upstream/10331; ENST00000420204/Downstream/13025;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/34611, chr9-CpG: 104/Downstream/52900
Upstream sequence
atgaaggacaaacgaagactttaaaaaacaaaaaaaatttgaggaagttcatcaccactatggtattctaaatattaaaccttatgggaaattctaaaga
Downstream sequence
ATTTTTAAAAAATGCTTATCGGATCATGTCAACtttttttttcttttggagatggagtctcactctgtcgcccaggctggagtgcagtggtgcaatctca
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate