NR3C2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003622
Fusion event
HBV-NR3C2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q31.23
Reference genome
GRCh37/hg19
Start
149025688/148104537 (Hg38)
End
149025688/148104537 (Hg38)
Location type
Intronic
Target gene
NR3C2
miRNAs that regulate target gene
hsa-mir-19b-3p ; hsa-mir-135a-5p ; hsa-mir-124-3p ; hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-944 ; hsa-mir-548i ; hsa-mir-301b-3p
Nearest miRNA
hsa-mir-12113/Upstream/321869; hsa-mir-1305/Downstream/4384790;
Nearest TSS
ENST00000502981/Upstream/39297; ENST00000514843/Downstream/41934;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/371770, chr4-CpG: 294/Downstream/337523
Upstream sequence
cctctttgcagccgagaataatGagggttggggttagggttagggttagggtgagggtgagggtgagggtgagggtgagggtgagggttagggttagggg
Downstream sequence
GTGAGAGAGAATGTGGCTTTGAATCTCGATCTCTCGATGTCTCTTACATACACATTCATGGTACTACCAGCTCTGGGTACTTTATTACAGACATAGAAGC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate