SP3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003624
Fusion event
HBV-SP3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
174836583/173971855 (Hg38)
End
174836583/173971855 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA2G
Target gene
SP3
miRNAs that regulate target gene
hsa-mir-27a-3p ; hsa-mir-223-3p ; hsa-mir-124-3p ; hsa-mir-484 ; hsa-mir-1260b ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-128-1/Upstream/5388837; hsa-mir-10b/Downstream/1195778;
Nearest TSS
ENST00000437798/Upstream/3504; ENST00000563759/Downstream/41120;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/6206, chr2-CpG: 36/Downstream/40982
Upstream sequence
CATTGAAATCACATTTATTGAACCCTGCTCTACAAGATGCTGCATGGTCCCTATCCTCAAGGAGTGGATATCCAGTTAAGAAACAAAATATAGggctggg
Downstream sequence
cacggtggctcacaccggtaatcccagcaccttgggaggccaaggcgggtggattgggaggccgaggcagatggatcacgaggtcaagagatggagaccg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate