Basic Information
VIS ID
TVIS10003633
Fusion event
HBV-chr17 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr17
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
63226018/65229900 (Hg38)
End
63226018/65229900 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/407798; hsa-mir-1250/Downstream/1557172;
Nearest TSS
ENST00000595228/Upstream/41196; ENST00000579474/Downstream/227641;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/106312, chr17-CpG: 66/Downstream/306937
Nearby gene
RGS9(-2197) ; AXIN2(+298665) ;
Nearest cancer related gene
AXIN2(TSG, +298665) ;
Upstream sequence
AGGGCAGTCCAGGTCATGGGCTGGAAGTGAATGGAGGCCAGGGAAGAGAAAAAAAAATCCAACAACCAATAAATTTTTTTATCTTGTTGCTCCACCCATC
Downstream sequence
CCCTGGTCACAAGTATGAtgctcctccatcttgtctggacattagaatccactggggaaacttgaaagatcccgctgtccagggcacacgcacagagctg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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