Basic Information
VIS ID
TVIS10003656
Fusion event
HBV-SHLD2P1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
46889180/46660435 (Hg38)
End
46889180/46660435 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA10G
Target gene
SHLD2P1
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1265/Upstream/1496347; hsa-mir-107/Downstream/2325077;
Nearest TSS
ENST00000439456/Upstream/28048; ENST00000506881/Downstream/250961;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/24588, chr10-CpG: 93/Downstream/113950
Upstream sequence
ACCCCTGGCACCTACCTGTGAGTTCATGATTACTAGTTTTAAAGTTCAGTCCTTTTTAtttttacttttttttttttttttttttttttagagacagtgt
Downstream sequence
ctcactctgtcatccaggctggagtgcagtggcacaatcacggcttactgtagccttgatctcccaggctcaggtgatcctttcacttcagcctcctgag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate