Basic Information
VIS ID
TVIS10003689
Fusion event
HBV-chr7 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q31.31
Reference genome
GRCh37/hg19
Start
118409427/118769373 (Hg38)
End
118409427/118769373 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/1749054; hsa-mir-10399/Downstream/8288715;
Nearest TSS
ENST00000635602/Upstream/529398; ENST00000421825/Downstream/1138002;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/554706, chr7-CpG: 93/Downstream/1503413
Nearby gene
ANKRD7(-526643) ; KCND2(+1504295) ;
Upstream sequence
CATAGGGTGGTATGTGCCAGCCATTTATTTCATCTTCACTCTTCCATTCTTCCCAGCAGGGGTGGCCAGCTTCATGGTTCATGAGCAGGAAACAGAGGCA
Downstream sequence
GAAAATTGCAGTGAGCTACTTAAAAGCAGAACCGTTGAATGGAACTTGTCTTATAACAGAACCAGTTTTAAATGGACAATTGTATACCTTAGAGCTGTCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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