Basic Information
VIS ID
TVIS10003705
Fusion event
HBV-chr10 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Reference genome
GRCh37/hg19
Start
135524749/135524749 (Hg38)
End
135524749/135524749 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/2153086;
Nearest TSS
ENST00000439456/Upstream/1897954;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/1763502, None/Downstream
Nearby gene
DUX4L7(-26291) ;
Upstream sequence
ggtgagggtgagggttagggtgagggttagggttagggttagggtgagggttagggttagggtgagggttagggttagggtgagggttagggttagggNN
Downstream sequence
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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