Basic Information
VIS ID
TVIS10003708
Fusion event
HBV-chr17 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
15804205/15900891 (Hg38)
End
15804205/15900891 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA17A
Nearest miRNA
hsa-mir-1253/Upstream/649195; hsa-mir-10226/Downstream/381123;
Nearest TSS
ENST00000595228/Upstream/83149; ENST00000582124/Downstream/44026;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/113978, chr17-CpG: 56/Downstream/16415
Nearby gene
MEIS3P1(-111186) ; ADORA2B(+44026) ;
Upstream sequence
CAATCTTTAAAAGTGAAGTTCTGCAGCGTTTCCCAGATCTTAGAAAGTGTTCCTCCTCGGCCACCATGTAAGGAAAGCGTCTTAGCCAGCCCAATTGCAA
Downstream sequence
GTGTGAGCAATTCCCCACAGAAAGAATTTGGTGAGGGAGAATATGTGACATCGCTGTTGTAAAAACAGTCAGAACGTGTGTCCCCAGGACTGCCATGTCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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