Basic Information
VIS ID
TVIS10003719
Fusion event
HBV-chr9 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
42734895/65267534 (Hg38)
End
42734895/65267534 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA9F
Nearest miRNA
hsa-mir-101-2/Upstream/24033699; hsa-let-7a-1/Downstream/5542441;
Nearest TSS
ENST00000422679/Upstream/16708; ENST00000464913/Downstream/17675;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/8398, chr9-CpG: 110/Downstream/15347
Nearby gene
FOXD4L4(-14553) ; PRPF31(+109475) ;
Upstream sequence
AAGATTCTTGGGCCAAGTGTGAGAGGGCAGAGAAGAACTGGGGCCTTCCTGGGCACTCACAGAGGTGCTGGTCCAGGCCCAGATGGAGCAGACAGGTGAA
Downstream sequence
TCATATACAGACTCTCTTGGATTCCTTACCAATTGCTTGAGAGATCACAGTGGGTTTGTGGGGAAAAAGTTTTCAAGATGATGGATCTTTCCCAACTTCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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