Basic Information
VIS ID
TVIS10003756
Fusion event
HBV-XRCC6P1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q23.33
Reference genome
GRCh37/hg19
Start
94967163/93207406 (Hg38)
End
94967163/93207406 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
XRCC6P1
Nearest miRNA
hsa-mir-107/Upstream/3614579; hsa-mir-1287/Downstream/2856909;
Nearest TSS
ENST00000439456/Upstream/131073; ENST00000445435/Downstream/116269;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/131907, chr10-CpG: 54/Downstream/288970
Nearby gene
CYP26A1(-129522) ; MYOF(+99023) ;
Upstream sequence
TCTTGTCCATCTACTCTGGAGTTGCCATGACCTTTTCAGTAAAGGGCATATTCgccgggcgcggtggcttatgcctataatcccagcactttgggaggta
Downstream sequence
gaggcgggcggatcacctgaggtcaggagttcaagaccagactggccaacatggtgaaaccccatctctactaaaaatacaaaaaattagctgggcatgg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate