Basic Information
VIS ID
TVIS10003762
Fusion event
HBV-chr19 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
q12
Reference genome
GRCh37/hg19
Start
30843061/30352154 (Hg38)
End
30843061/30352154 (Hg38)
Location type
Intronic
Target gene
LOC110120875 ; ZNF536
Nearest miRNA
hsa-mir-10395/Upstream/9952800; hsa-let-7e/Downstream/4770546;
Nearest TSS
ENST00000633603/Upstream/123439; ENST00000355537/Downstream/20258;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/123091, chr19-CpG: 90/Downstream/22622
Nearby gene
URI1(-335542) ; ZNF536(+20267) ;
Upstream sequence
ATAGAGCACAAGGAGTGAGAAAATAAAGTGGAGGTTGTCAGAAGTGGCAGCTGCTTGGAATCCTGATAAATATAAGCTTTTATTGATCTGATGAAAATGA
Downstream sequence
AAGATCCCAGTGCTAGGCAGTATTTAGCTTCTTGTCTACAGCACGTCACCGGTGGCCTTGCATGGGGATAGATTTCCATTCTCATACACCGGATTTGATT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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