Basic Information
VIS ID
TVIS10003764
Fusion event
HBV-chr20 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr20
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
54484314/55909258 (Hg38)
End
54484314/55909258 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/1840773; hsa-mir-1-1/Downstream/1412244;
Nearest TSS
ENST00000382410/Upstream/404043; ENST00000243911/Downstream/96214;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/1432804, chr20-CpG: 165/Downstream/94289
Nearby gene
SREBF2-AS1(-440579) ; CBLN4(+88099) ;
Upstream sequence
AGAACAGCATAAAGGTGTATTTTATTCATTCTTTTATCTGTTAAATATTTATCAGGCAAAAGCTCCACTTGCTCAAATATAAGAATCTAATGATGGGTAT
Downstream sequence
TAACACTCTCTCAGCTCATGACAACACAAGTCAAATGAAAAAAAACAAGTGAATAATTACATATGTGACTTATAGATTAGCTGAACTCTTTGAAATGTTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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