Basic Information
VIS ID
TVIS10003818
Fusion event
HBV-LINC01412 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
145312211/144554644 (Hg38)
End
145312211/144554644 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2K
Target gene
LINC01412
Nearest miRNA
hsa-mir-128-1/Upstream/3967959; hsa-mir-10b/Downstream/4775634;
Nearest TSS
ENST00000437798/Upstream/30061; ENST00000413525/Downstream/11791;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/30156, chr2-CpG: 49/Downstream/2032589
Nearby gene
ZEB2-AS1(-33746) ; TEX41(+113323) ;
Upstream sequence
CTGGTACAAATTGACATGCACAGCACAAGATTGGCACTATGCAACAGCCGATCTGGGAAAATACAGGAATTCCTAGCCAGACCAAAATATGAGGTCAAGG
Downstream sequence
AAGTTGCTTTTATAATAATAGTGGTTATCTGTTTAATGTGTGATCTGGCAGTGATATGATGTTGACCATAGGCAATTATGCATATTTCTAAACTGGTTGT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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