Basic Information
VIS ID
TVIS10003819
Fusion event
HBV-PAXIP1-AS2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q36.2
Reference genome
GRCh37/hg19
Start
154724269/154932559 (Hg38)
End
154724269/154932559 (Hg38)
Location type
ncRNA_intronic
Fragile sites / regions
FRA7I
Target gene
PAXIP1-AS2
Nearest miRNA
hsa-mir-10399/Upstream/3498920; hsa-mir-153-2/Downstream/2641777;
Nearest TSS
ENST00000635602/Upstream/4031; ENST00000608064/Downstream/18667;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/17780, chr7-CpG: 174/Downstream/69748
Upstream sequence
CTCCATCCACCTCCATCCCAGCTCCACCTCATCTCCATCCACAAATCCATCCCAGCTCTATCCATCTCCATTGTATCTCCATCCAGTTCCATCCAGATGC
Downstream sequence
gtgcccaccaccacgcctggctaattttttgtatttttagtagagacagggtttcaccattttagccaggatggtctcgaactcctgaccttgtgatcct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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