VISDB Viral Integration Site DataBase

VIS ID

TVIS10003828

Fusion event

HBV-chr5 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr5

Cytoband

q31.3

Reference genome

Start

End

140999357/141619790 (Hg38)

Location type

Promoter;downstream

Target gene

DIAPH1 ; HDAC3

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-615-3p ; hsa-mir-328-3p ; hsa-mir-320a ; hsa-mir-185-5p ; hsa-mir-27b-3p ; hsa-mir-23b-3p ; hsa-mir-92a-3p ; hsa-mir-18a-5p ; hsa-let-7e-5p ; hsa-mir-7110-3p ; hsa-mir-2355-3p ; hsa-mir-4646-3p ; hsa-mir-4433b-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-342-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-1228-3p ; hsa-mir-6800-3p ; hsa-mir-3674 ; hsa-mir-502-5p ; hsa-mir-2467-5p ; hsa-mir-2116-3p ; hsa-mir-4459 ; hsa-mir-4695-5p ; hsa-mir-1306-5p ; hsa-mir-1178-5p ; hsa-mir-1233-5p ; hsa-mir-127-5p ; hsa-mir-1293 ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-1972 ; hsa-mir-2278 ; hsa-mir-297 ; hsa-mir-3677-5p ; hsa-mir-3928-5p ; hsa-mir-3944-5p ; hsa-mir-424-5p ; hsa-mir-4483 ; hsa-mir-4501 ; hsa-mir-4524b-3p ; hsa-mir-4690-5p ; hsa-mir-4701-5p ; hsa-mir-497-5p ; hsa-mir-4999-5p ; hsa-mir-541-3p ; hsa-mir-567 ; hsa-mir-588 ; hsa-mir-654-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6778-5p ; hsa-mir-6806-3p ; hsa-mir-6823-5p ; hsa-mir-6838-5p ; hsa-mir-92a-2-5p

Nearest miRNA

hsa-mir-10397/Upstream/971864; hsa-mir-103a-1/Downstream/2060070;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/482, chr5-CpG: 111/Downstream/17074

Nearest cancer related gene

HDAC3(TSG, No orient, 0)

Upstream sequence

CTGGTTCGTAACCTTCAAAGTTAAAACCTGTGATACTTATCTGATGCTCCTCTGAGTTAGCCAATCACACTTGAAGCTGCTCAATACTGGGTAAGTTGCT

Downstream sequence

gaagtgacttgcccaagaacgcataattgatataaaatttaaacccagcttagtctgatttgctgccaaaccctatgttTAACCAGGATTCCCCACTGAC