Basic Information
VIS ID
TVIS10003838
Fusion event
HBV-chr10 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
110423/64483 (Hg38)
End
110423/64483 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-107/Downstream/577206;
Nearest TSS
ENST00000562162/Upstream/14894; ENST00000439456/Downstream/9680;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/15122, chr10-CpG: 57/Downstream/9186
Nearby gene
TUBB8(-15245) ; ZMYND11(+69982) ;
Nearest cancer related gene
ZMYND11(TSG, +69982) ;
Upstream sequence
accatgacccctaaccactgaccccaaccctaacccttaaccctaacccttaacccctaaccctaactctaaaaccctaaccccaaccccaacactaacc
Downstream sequence
cctaaccctaaccctcaccctcaccctcaccctaacccttaaccctaacactaaccatctaacccttctccataacttaaacctaaccattaccccaacc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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