Basic Information
VIS ID
TVIS10003871
Fusion event
HBV-BOD1L2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
54813064/57145833 (Hg38)
End
54813064/57145833 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA18B
Target gene
BOD1L2
Nearest miRNA
hsa-mir-1-2/Upstream/1666535; hsa-mir-122/Downstream/1305241;
Nearest TSS
ENST00000575820/Upstream/73714; ENST00000585477/Downstream/1165;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/23870, chr18-CpG: 154/Downstream/206643
Upstream sequence
CCATGTTGCCTGTCTTAAACAACAGCCACAGCAAACATTTATTGAGTGTTAGACTGGGCCAGGCACGTGGAGAGCTCCAtaaagcttagcacagggccac
Downstream sequence
atcgactagtccctcaataaatattgattaATTTAAAAAAATACAGAACTGAATTGTCGAGCTGATCATGGGGATGGTGAGGAGCATAGGTAGGGGGTTG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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