Basic Information
VIS ID
TVIS10003881
Fusion event
HBV-chr6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
30056259/30088482 (Hg38)
End
30056259/30088482 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-3143/Upstream/2940794; hsa-mir-10398/Downstream/495850;
Nearest TSS
ENST00000381078/Upstream/12595; ENST00000440874/Downstream/16758;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/12759, chr6-CpG: 30/Downstream/12233
Nearby gene
RNF39(-12631) ; TRIM31(+14415) ;
Nearest cancer related gene
TRIM31(TSG, +14415) ;
Upstream sequence
CTGTATCCTGTCATTTTAATTGGAAGAAGTATGGCCTAATGGAAATGTTCAATGTTCTTTTTTTTTTCTTTTCTTTTAATCTGTTAGTGCTGCCAACTGT
Downstream sequence
AGGATGTCCTAACTGGTTTATTGGCTTCAAGGTCAATCACCATAGGTCAGTAGTGCTGCAGCTACTGCTAGCATAGCAGCCACGGGCCCAGCTGCCCTAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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