Basic Information
VIS ID
TVIS10003888
Fusion event
HBV-chr8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
40961100/41103581 (Hg38)
End
40961100/41103581 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/11146233; hsa-mir-10400/Downstream/167467;
Nearest TSS
ENST00000518652/Upstream/201727; ENST00000521725/Downstream/203409;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/205696, chr8-CpG: 148/Downstream/204752
Nearby gene
ZMAT4(-205757) ; SFRP1(+158376) ;
Nearest cancer related gene
SFRP1(TSG, +158376) ;
Upstream sequence
ACAAATATGGAATTTAATCTTGTAATGGTTTCCTCTTGGTGGCATATGTAGACCTAATTCCCAAATTTTTAGAAATTTTCTGTTTCTGTTAAGCGTGAGC
Downstream sequence
cgcctcctgggttcaagcaattctcctgcctcagcctcccaagtagctgagactacaggtgcataccaccatgccgtgctaattattgtatttttagtag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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