Basic Information
VIS ID
TVIS10003901
Fusion event
HBV-chr6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
62113614/61124098 (Hg38)
End
62113614/61124098 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/3733886; hsa-mir-10524/Downstream/10252862;
Nearest TSS
ENST00000381078/Upstream/400950; ENST00000370659/Downstream/1162129;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/3162548, chr6-CpG: 45/Downstream/1161852
Nearby gene
MTRNR2L9(+170394) ;
Upstream sequence
GACATTCAAGGTAATTTATACTTTCTTTCAAAACGTAGGGAGAGTTAGTAATCCTTTACTCCAGCAAATATAAAGATCACTTGCAAAAATGAAAATTGAC
Downstream sequence
AGTCCCAAATGTAGTGTCTGGGCACCTGTCAGTAATAATGAGTCAAAGAAAAAAGAGCAGGGGCGTAACTTGGGCGATGTGATCAGAGGAGAAATACCCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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