Basic Information
VIS ID
TVIS10003908
Fusion event
HBV-chr7 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
64942005/65477092 (Hg38)
End
64942005/65477092 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA7J
Nearest miRNA
hsa-mir-1183/Upstream/797916; hsa-mir-10399/Downstream/1637230;
Nearest TSS
ENST00000635602/Upstream/14021; ENST00000434382/Downstream/396175;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/102792, chr7-CpG: 168/Downstream/31415
Nearby gene
ZNF92(-75957) ; LOC441242(+169919) ;
Upstream sequence
CACAGGGGGAGCTGCAGACAGACATGGGAGGAGCCGCAGACACGGGGAGCCGCAGACACAGGGAGCCGCAGACACAGGGGGAGCCGCAGACACAGGAGGA
Downstream sequence
atcatcacaatcctccaccatatgctcccgctcctgccttacctctttcccctcctctctccaaccacccagattctgattctaattcctccccatctcc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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