VISDB Viral Integration Site DataBase

VIS ID

TVIS10003911

Fusion event

HBV-TNRC6B integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr22

Cytoband

q13.1

Reference genome

Start

End

40482595/40086591 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-183-5p ; hsa-mir-7-5p ; hsa-mir-103a-3p ; hsa-mir-32-5p ; hsa-mir-21-5p ; hsa-mir-19b-3p ; hsa-mir-18a-5p ; hsa-mir-16-5p ; hsa-mir-1229-3p ; hsa-mir-744-5p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-125b-5p ; hsa-mir-23b-3p ; hsa-mir-222-3p ; hsa-mir-99a-5p ; hsa-mir-31-5p ; hsa-let-7b-5p ; hsa-mir-18b-5p ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-1297 ; hsa-mir-4465 ; hsa-mir-5697 ; hsa-mir-29b-1-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-603 ; hsa-mir-543 ; hsa-mir-3658 ; hsa-mir-3941 ; hsa-mir-6757-3p ; hsa-mir-8485 ; hsa-mir-19a-3p ; hsa-mir-1249-5p ; hsa-mir-6797-5p ; hsa-mir-4269 ; hsa-mir-3150b-3p ; hsa-mir-4784 ; hsa-mir-6715b-5p ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-548at-5p ; hsa-mir-1321 ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-561-3p ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-15a-5p ; hsa-mir-107 ; hsa-mir-15b-5p ; hsa-mir-186-3p ; hsa-mir-195-5p ; hsa-mir-378a-5p ; hsa-mir-330-3p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-4310 ; hsa-mir-4729 ; hsa-mir-6838-5p ; hsa-mir-7157-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-891b ; hsa-mir-5586-5p ; hsa-mir-6849-3p ; hsa-mir-4781-3p ; hsa-mir-3120-3p ; hsa-mir-148a-3p ; hsa-mir-130a-3p ; hsa-mir-152-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-148b-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-3688-3p ; hsa-mir-4643 ; hsa-mir-506-3p ; hsa-mir-124-3p ; hsa-mir-5186 ; hsa-mir-1-5p ; hsa-mir-4753-5p ; hsa-mir-513a-5p ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-101-5p ; hsa-mir-3151-5p ; hsa-mir-6721-5p ; hsa-mir-486-3p ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-6804-5p ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-1825 ; hsa-mir-759 ; hsa-mir-500b-3p ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-6515-5p ; hsa-mir-7847-3p ; hsa-mir-7106-5p ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-4533 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-1252-5p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-6807-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-3653-3p ; hsa-mir-299-5p ; hsa-mir-4511 ; hsa-mir-548b-3p ; hsa-mir-6863 ; hsa-mir-210-3p ; hsa-mir-4776-5p ; hsa-mir-3619-3p ; hsa-mir-3654 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-2682-3p ; hsa-mir-6877-3p ; hsa-mir-6819-3p ; hsa-mir-548c-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-744-3p ; hsa-mir-6868-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-5096 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-197-3p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-302a-5p ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-627-3p ; hsa-mir-4742-5p ; hsa-mir-4433a-3p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-1197 ; hsa-mir-4436a ; hsa-mir-4459 ; hsa-mir-4519 ; hsa-mir-4779 ; hsa-mir-5000-3p ; hsa-mir-92a-2-5p ; hsa-mir-129-5p ; hsa-mir-2113 ; hsa-mir-329-5p ; hsa-mir-4464 ; hsa-mir-4748 ; hsa-mir-5010-3p ; hsa-mir-6509-5p

Nearest miRNA

hsa-mir-1286/Upstream/2097738; hsa-let-7a-3/Downstream/727292;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/40785, chr22-CpG: 31/Downstream/259808

Upstream sequence

atgatgatatgtttaggttcatcttatgcatcttctgtctcagccctcagtcatttcttcagggagctctcgttcttttcagcaggaaaggatatatgga

Downstream sequence

ggcacatttggatgctTGAACAATGGATGACAGACTTTTTAATAGATACTTATCAGAATATCTGTAGAGTTCAAAAGATGTCTTCTTTCACCTTGAATTT