LYST _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003920
Fusion event
HBV-LYST integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q42.3
Reference genome
GRCh37/hg19
Start
235966226/235802926 (Hg38)
End
235966226/235802926 (Hg38)
Location type
Exonic
Fragile sites / regions
FRA1H
Target gene
LYST
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-93-5p ; hsa-mir-92b-3p ; hsa-mir-193a-3p ; hsa-mir-26a-5p
Nearest miRNA
hsa-mir-101-1/Upstream/612810; hsa-mir-1537/Downstream/50074;
Nearest TSS
ENST00000473358/Upstream/14078; ENST00000412098/Downstream/36557;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/151738, chr1-CpG: 113/Downstream/63361
Upstream sequence
aagtggtattattatGAACCATTTTGCTATTTAATGATCTGGCTTGCAGATCTAATTACAAGCACTTCAATGATATTTTACCATCATCCTGGGTTTCGCC
Downstream sequence
ATCTTCAGGATTGCTTTCACTATCTGCTTCGTAACCTTCTTCTTCAACTAAAAGTTTAAAACTACAACACTGAGAATCCTCAGCTTCTTCTGAAAAATCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate