VISDB Viral Integration Site DataBase

VIS ID

TVIS10003923

Fusion event

HBV-chr6 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr6

Cytoband

q14.1

Reference genome

Start

End

75956171/75246455 (Hg38)

Location type

Promoter;downstream

Fragile sites / regions

Target gene

COX7A2 ; TMEM30A

miRNAs that regulate target gene

hsa-mir-128-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-27a-3p ; hsa-mir-26b-5p ; hsa-mir-877-5p ; hsa-mir-548b-3p ; hsa-mir-148b-3p ; hsa-mir-4799-5p ; hsa-mir-590-3p ; hsa-mir-4775 ; hsa-mir-5011-5p ; hsa-mir-136-5p ; hsa-mir-3591-5p ; hsa-mir-4671-3p ; hsa-mir-4473 ; hsa-mir-3152-3p ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-512-3p ; hsa-mir-32-3p ; hsa-mir-4282 ; hsa-mir-4480 ; hsa-mir-4696 ; hsa-mir-6875-5p ; hsa-mir-3126-5p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-7845-5p ; hsa-mir-6873-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-548g-3p ; hsa-mir-548av-3p ; hsa-mir-3144-3p ; hsa-mir-4735-5p ; hsa-mir-7705 ; hsa-mir-100-5p ; hsa-mir-99a-5p ; hsa-mir-99b-5p ; hsa-mir-129-5p ; hsa-mir-656-3p ; hsa-mir-190a-3p ; hsa-mir-548l ; hsa-mir-548n ; hsa-mir-3713 ; hsa-mir-6793-3p ; hsa-mir-5011-3p ; hsa-mir-182-3p ; hsa-mir-5694 ; hsa-mir-383-5p ; hsa-mir-28-3p ; hsa-mir-3936 ; hsa-mir-26a-5p ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p

Nearest miRNA

hsa-mir-10398/Upstream/2278702; hsa-mir-10524/Downstream/181952;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/39784, chr6-CpG: 63/Downstream/37832

Upstream sequence

GACCCCAGTTGATGtataatttttaaatatttaatagaaactttaaaatattGGAAAAATTAATCTTACATTGTCACATTGCTCATTCTGAACTGTCAGC

Downstream sequence

tgttcagattatgtcaaaagcctttttaacgggtttccctgtttccactcttccactatcttccacacagcaatgattcttttaagaacttaagctggat