Basic Information
VIS ID
TVIS10003927
Fusion event
HBV-LINC02703 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
115804929/115934211 (Hg38)
End
115804929/115934211 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA11G ; FRA11B
Target gene
LINC02703
Nearest miRNA
hsa-mir-10392/Upstream/2484123; hsa-let-7a-2/Downstream/2709789;
Nearest TSS
ENST00000527297/Upstream/1354; ENST00000439483/Downstream/566419;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/173812, chr11-CpG: 30/Downstream/566331
Nearby gene
LINC00900(-174011) ; BUD13(+813957) ;
Upstream sequence
TTTTCATTTCACCTAGTTGTTGTGGACATTGTGCTGACACACCTAAGGGTGGTTTGGAAACAGTTGGCATGTTTTCTTTATGTATTTTTCACCTCTGCCA
Downstream sequence
TCTGTAACTGAGAAAGGGTATCCTTCCTCCTGCCAGTTCTCCCCAGCTGAAGTCTACACAATCTTTACCCAGACATCAGAAACAGCTGTCTCAGGCAGAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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