Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003928
Fusion event
HBV-PCTP integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
Start
End
53825396/55748035 (Hg38)
Location type
Promoter
Target gene
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-32-5p ; hsa-mir-125b-5p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-125a-5p ; hsa-mir-670-5p ; hsa-mir-4319 ; hsa-mir-4324 ; hsa-mir-4282 ; hsa-mir-3681-3p ; hsa-mir-4446-5p ; hsa-mir-4528 ; hsa-mir-4672 ; hsa-mir-4789-5p ; hsa-mir-5694 ; hsa-mir-6768-5p ; hsa-mir-8062 ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-4732-3p ; hsa-mir-345-3p ; hsa-mir-382-3p ; hsa-mir-6508-5p ; hsa-mir-3916 ; hsa-mir-5011-3p ; hsa-mir-6815-3p ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-135b-5p ; hsa-mir-135a-5p ; hsa-mir-5700 ; hsa-mir-5680 ; hsa-mir-5692a
Nearest miRNA
hsa-mir-10226/Upstream/4979305; hsa-mir-1250/Downstream/1143235;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/186432, chr17-CpG: 32/Downstream/3026
Upstream sequence
TCTGATCTTGCCCTCCCTTGTTCCAGGTTTCTGTAGGTTAGAACTTTTGTTCCACTTTATTTTTATATGTGCCTTTTTTTTCTGTATTCTCCCCACCCAC
Downstream sequence
CCATCCCATCCCCTGGCCTCTTTATTCTCTGATTATTGGGCTTCAGTAAGAAGTGTTTAGCcttttcaatgtgtccttcgtgtttcttaattactctttc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.