Basic Information
VIS ID
TVIS10003931
Fusion event
HBV-chr16 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
9757988/9664131 (Hg38)
End
9757988/9664131 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/4031565; hsa-mir-11401/Downstream/1642309;
Nearest TSS
ENST00000527434/Upstream/122086; ENST00000636913/Downstream/12712;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/571299, chr16-CpG: 282/Downstream/515955
Nearby gene
MIR7641-2(-99740) ; GRIN2A(+89277) ;
Nearest cancer related gene
GRIN2A(TSG, +89277) ;
Upstream sequence
TCCCAAAAGCAACTGGTGAAAGAAAAGTACATCCTGGGAAGGGGAACTGGGCCGGGGGCATAGAGTTGTCACAGAGGTCTGGACCCAAACAGCTGGGGTG
Downstream sequence
AAAGCCCTGACTTGGTAACAGGGTGACTCCAGGAAAGTGTGTTAATCATTTTGCACCTGTTTTGTCTGAGTTTTAAATTAaaggtgcttagcagagtgtc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate