Basic Information
VIS ID
TVIS10003936
Fusion event
HBV-LINC00944 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
127258028/126773482 (Hg38)
End
127258028/126773482 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA12E
Target gene
LINC00944
Nearest miRNA
hsa-let-7i/Upstream/1857823; hsa-mir-3612/Downstream/1520610;
Nearest TSS
ENST00000382841/Upstream/1071; ENST00000543451/Downstream/101168;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/45499, chr12-CpG: 78/Downstream/372484
Upstream sequence
ACCACTGCACAGAAGACTCCTAGGCTGATAAGAATGTGTGAAGATGACCTGCAGATGAATATGCAAAGGAGAGTGCATGGAGACCACCAGCAGAGGACTA
Downstream sequence
AATTAGAAGAAACAATCTGGAAGGGTGCAGGCACTGGTTTGGCTGCCATTAGTCTGAAATCCATACAGGAATTCAGAGGGGAGACACATGTTGCTAGAGA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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