Basic Information
VIS ID
TVIS10003945
Fusion event
HBV-chr4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
GRCh37/hg19
Start
109209897/108288741 (Hg38)
End
109209897/108288741 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/6958327; hsa-mir-1243/Downstream/1199957;
Nearest TSS
ENST00000502981/Upstream/119785; ENST00000503574/Downstream/331654;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/115351, chr4-CpG: 30/Downstream/361796
Nearby gene
LEF1-AS1(-112311) ; RPL34-AS1(+249449) ;
Upstream sequence
agTGAGTGTAGGTGAGGAAGGGGAGAGTCACTCCAGGAAAAGTGCCTCTGAGGAGCAGGGCTCTGTGGGACAAGGAATGGCATTCCAAATAGGCCAACAT
Downstream sequence
AGGCACACTCAACCACAGCTGACTACTACTTACCTGGATGGAAAATTTAAACTTAACCATTTATTAGTGTACAAACCAAGAATTGGGAGCATAATTTTGG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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