Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003946
Fusion event
HBV-ACSL3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q36.1
Reference genome
End
223743258/222878540 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-340-5p ; hsa-mir-375 ; hsa-mir-221-3p ; hsa-mir-100-5p ; hsa-mir-377-5p ; hsa-mir-6086 ; hsa-mir-655-5p ; hsa-mir-96-3p ; hsa-mir-329-5p ; hsa-mir-551b-5p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-26a-1-3p
Nearest miRNA
hsa-mir-10b/Upstream/2971975; hsa-mir-1244-1/Downstream/2131921;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/16835, chr2-CpG: 33/Downstream/174318
Upstream sequence
TTCTCTGCAGCCTTGTTGACACTCCTGACAACAAGTGTTTGTCTTTGGCTTCTAGGGCACTGTTTCCTGTTCCTTTACCTTTCTTGTTGGTTCTTCTGGC
Downstream sequence
ATCTGCCCTTAATCCTTTATCCTACAATTGAATATACTGTTTCTGAGGAATTCTGTGTTCTATGAATAGAGTCAATGATGACTGTGACCTCTGCATCTTC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.