VISDB Viral Integration Site DataBase

VIS ID

TVIS10003966

Fusion event

HBV-PIK3R1 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr5

Cytoband

q13.1

Reference genome

Start

End

67576101/68280273 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-29a-3p ; hsa-mir-376a-3p ; hsa-mir-29b-3p ; hsa-mir-21-5p ; hsa-let-7a-5p ; hsa-mir-155-5p ; hsa-mir-503-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-646 ; hsa-mir-6838-5p ; hsa-mir-448 ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-190a-3p ; hsa-mir-4524a-5p ; hsa-mir-5011-5p ; hsa-mir-4524b-5p ; hsa-mir-221-3p ; hsa-mir-1277-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-4793-5p ; hsa-mir-3924 ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-455-5p ; hsa-mir-5580-3p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-6721-5p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-542-3p ; hsa-mir-218-1-3p ; hsa-mir-143-3p ; hsa-mir-128-3p ; hsa-mir-487a-3p ; hsa-mir-486-5p ; hsa-mir-1202 ; hsa-mir-126-3p ; hsa-mir-23a-3p ; hsa-mir-23b-3p ; hsa-mir-302a-5p ; hsa-mir-3658 ; hsa-mir-3972 ; hsa-mir-4317 ; hsa-mir-4755-3p ; hsa-mir-5006-5p ; hsa-mir-5007-5p ; hsa-mir-7856-5p ; hsa-mir-924

Nearest miRNA

hsa-mir-10397/Upstream/8576570; hsa-mir-103a-1/Downstream/3889194;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/63715, chr5-CpG: 26/Downstream/8112

Nearest cancer related gene

PIK3R1(OG, No orient, 0)

Upstream sequence

TTCAGTGAGGAAAAACCAAGACCAGAACCCCGATGAAGACCAAGATTTAAGGCATAGACAAGAAGCAGAATAGATAAAGGAGACAAGAGCTCATCTTCAG

Downstream sequence

GCCAGCACACCCTGAACAGCTTGTGGTTTCTTTACACACTGAGCTTTTTGCATTTCCATTTGACCTGAGATTTCTACTTTCTCATAATGCGTTTTCTAAT