GBA _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003993
Fusion event
HBV-GBA integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q22
Reference genome
GRCh37/hg19
Start
155211246/155241455 (Hg38)
End
155211246/155241455 (Hg38)
Location type
Intronic
Target gene
GBA
miRNAs that regulate target gene
hsa-mir-191-5p ; hsa-mir-4298 ; hsa-mir-1302 ; hsa-mir-4795-5p ; hsa-mir-4648 ; hsa-mir-1236-3p ; hsa-mir-4735-5p ; hsa-mir-6733-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p
Nearest miRNA
hsa-mir-101-1/Upstream/46183; hsa-mir-1182/Downstream/104895;
Nearest TSS
ENST00000473358/Upstream/180; ENST00000467204/Downstream/3151;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/13712, chr1-CpG: 39/Downstream/8836
Upstream sequence
TGTTACAGATTATATGCCCTATAAAACTCTGGAGGGCATGTATGGGTGACAACTTTAGGAAGAGCCTAGAACACAGATTTGCATGGAGAATGGGGTAGAG
Downstream sequence
GCTCCTAAATCCCAGAGGATGGGAACCACAGCAGGCACACTTCTTTTTTGATAGAAATGTCAAAAAGGTACAAATAAAGCTGATATAATTTAAAAAAAAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate