DDB2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004006
Fusion event
HBV-DDB2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
47257978/47236427 (Hg38)
End
47257978/47236427 (Hg38)
Location type
Intronic
Target gene
DDB2
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-26b-5p ; hsa-mir-675-5p
Nearest miRNA
hsa-mir-129-2/Upstream/56690; hsa-let-7a-2/Downstream/164543;
Nearest TSS
ENST00000527297/Upstream/1800; ENST00000614884/Downstream/1379;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/48802, chr11-CpG: 37/Downstream/12256
Nearest cancer related gene
DDB2(TSG, No orient, 0)
Upstream sequence
GCTTCTCTATCATTAGTCCCCAACACTAATAGCTTTCAAGTCCTTTGATGCCTTTTTGCCTAAGCCCCCATGCAGACTGAGCTCTGCTAGTTCTGCATTC
Downstream sequence
TTTTCCAAAACTACAGATCCTCTTCAGATCTTCAGGTTTTATGCCTATACTTCTCTGGTcagttcagaatagtggtggggagcgccagtttccagcagcc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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